Scientific Paper
Quartz Crystal Microbalance Assay of Clinical Calcinosis Samples and Their Synthetic Models Differentiates the Efficacy of Chelation-Based Treatments
Summary
Ground calcinosis samples from patients and synthetic hydroxyapatite were deposited on QCM sensors by electrophoresis and then dissolved by chelator solutions, with sub-second time resolution. Patient material and synthetic mimics dissolved alike, and at pH 7.4 and 37 °C EDTA removed the deposits more than twice as fast as citrate, a ranking confirmed on tablets.
Summary written by the openQCM team. The original abstract is on the publisher’s page.
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