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Scientific Paper

Neutron reflectometry and lung cancer in vitro study of the interaction between mesoporous magnetic nanocarriers and plasma membranes

Journal article 2026

Pavol Hrubovčák, Nicolò Paracini, Eva Beňová, Vladimir Zelenak, Gabriela Blašková, Anna Matiašová, Philipp Gutfreund, Adriana Zelenakova

SSRN Electronic Journal, 26, 2026

View at publisher ↗ Full text ↗

DOI 10.2139/ssrn.7284797

Summary

Neutron reflectometry, quartz crystal microbalance measurements and cell tests were combined to see whether magnetic nanocarriers (Fe3O4 clusters in a 40 nm mesoporous silica shell) damage cell membranes. Supported DMPC bilayers were left intact even under a magnetic field, and A549 lung cancer cells took up the particles without significant harm over 24 hours.

Summary written by the openQCM team. The original abstract is on the publisher’s page.

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