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Scientific Paper

Elliptical Electrode Designs in Quartz Crystal Microbalances: Enhancing Sensitivity in Liquid Biosensing Applications

Journal article 2025

Afri Ahamed, Chien Wei Ooi, Hui Jean Lim, N. Ramakrishnan, Tridib Saha

Sensors and Actuators A: Physical, 387, 116392, 2025

View at publisher ↗ Full text ↗

DOI 10.1016/j.sna.2025.116392

Summary

Elliptical electrodes on QCM crystals, combined with a single-droplet assay, make liquid biosensing more sensitive while using less sample. With molecularly imprinted polydopamine films that recognise pepsin, the elliptical design gave up to ten times the sensitivity of the standard one-inch circular crystal and stayed linear over a wider droplet volume range (250 Hz/µL against 50 Hz/µL).

Summary written by the openQCM team. The original abstract is on the publisher’s page.

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