@inproceedings{10.1117/12.3016099,

title = {Detection and confirmation of Salmonella Typhimurium by smartphone-enabled optomechanical platform},

author = {Hyun Jung Min and Hansel A. Mina and Sungho Shin and Iyll-Joon Doh and J. Paul Robinson and Bartek Rajwa and Amanda J. Deering and Euiwon Bae},

editor = {Moon S. Kim and Byoung-Kwan Cho},

url = {https://doi.org/10.1117/12.3016099},

doi = {10.1117/12.3016099},

year  = {2024},

date = {2024-06-06},

urldate = {2024-01-01},

booktitle = {Sensing for Agriculture and Food Quality and Safety XVI},

volume = {13060},

pages = {130600H},

publisher = {SPIE},

organization = {International Society for Optics and Photonics},

abstract = {\textit{Salmonella} ser. Typhimurium is notorious for causing serious foodborne illnesses and presenting considerable public health risks. The study introduces an innovative system based on a quartz crystal microbalance, designed to detect the target pathogen by integrating the system around a smartphone. The system operates through a dual-mode approach, relying on two distinct mechanisms: measuring frequency changes due to variations in bacterial mass and quantifying fluorescence intensities resulting from bacteria captured by FITC-labeled antibodies. Incorporating FITC-labeled antibodies not only enhances the resonance frequency shift but also offers visual confirmation through the fluorescence signal. The integration of the quartz crystal microbalance system with a smartphone enables real-time monitoring. This system displays both frequency and temperature data, while also capturing fluorescence intensities to estimate the concentration of the target analyte. The smartphone-based system successfully detected \textit{Salmonella }Typhimurium within a concentration range of 10^{5} CFU/mL after the application of FITC-labeled antibodies. This portable QCM system represents a promising advancement in pathogen detection, holding significant potential to improve food safety protocols and strengthen public health safeguards.},

keywords = {Antibody immobilization, openQCM, Portable device, QCM, Quartz Crystal Microbalance, Salmonella Typhimurium, Smartphone based detection method},

pubstate = {published},

tppubtype = {inproceedings}

}