Scientific Paper
Hyaluronic Acid-Coated Solid Lipid Nanoparticles-Functionalized Quartz-Crystal Microbalance (QCM) Immunosensor for Label-Free Haptoglobin Detection: Toward Monitoring of Neuroinflammation
Summary
An immunosensor that measures haptoglobin, an inflammation marker linked to neurodegenerative disease, in human serum rather than cerebrospinal fluid. The crystal of a custom QCM-R instrument carries a PEG monolayer, hyaluronic acid-coated solid lipid nanoparticles and anti-haptoglobin antibodies, reaching a detection limit of about 0.063 µg/mL with high reproducibility.
Summary written by the openQCM team. The original abstract is on the publisher’s page.
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