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Scientific Paper

Development of Aptamer-Based Non-labeling Methods

Journal article 2018

Huajie Gu, Liling Hao, Zhouping Wang

Aptamers for Analytical Applications: Affinity Acquisition and Method Design, 301–343, 2018

View at publisher ↗

DOI 10.1002/9783527806799.ch11

Summary

A book chapter on label-free methods for aptamers: surface plasmon resonance, quartz crystal microbalance, isothermal titration calorimetry and microscale thermophoresis. It explains their principles and their use for detection and binding affinity, noting that avoiding labels leaves the aptamer’s structure, and so its affinity and specificity, unchanged.

Summary written by the openQCM team. The original abstract is on the publisher’s page.

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