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Scientific Paper

Aptamer-Based Quartz Crystal Microbalance Biosensor for Histamine

Journal article 2025

George Rabacal, Lyam Estipona, Dharmatov Rahula B. Albano

Acta Manilana, 73, 67–79, 2025

View at publisher ↗

DOI 10.53603/actamanil.73.2025.bsdk9365

Summary

A QCM biosensor for histamine, a marker of fish spoilage and allergic reactions, in which a thiol-modified aptamer is anchored to the gold electrode. After optimising pH, aptamer concentration and immobilisation time, it responded linearly from 0.01 to 1 mg/L with a 0.0071 mg/L detection limit, and recovered 99–109% of histamine spiked into fish sauce.

Summary written by the openQCM team. The original abstract is on the publisher’s page.

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