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Scientific Paper

A quartz crystal microbalance biosensor based on polyethylenimine-modified gold electrode to detect hepatitis B biomarker

Journal article 2022

Zahra Saffari, Mina Sepahi, Reza Ahangari-Cohan, Mehdi Khoobi, Mojtaba Hamidi-Fard, Amir Ghavidel, Mohammad Reza Aghasadeghi, Dariush Norouzian

Analytical Biochemistry, 661, 114981, 2022

View at publisher ↗ Full text ↗

DOI 10.1016/j.ab.2022.114981

Summary

A QCM immunosensor for the hepatitis B surface antigen, built by attaching antibodies to a gold electrode modified with polyethylenimine and optimised by response surface methodology. It covers 1 to 1000 ng/mL with a detection limit of about 3 ng/mL, works in human serum with results close to ELISA and around 91% recovery, and can be fully regenerated.

Summary written by the openQCM team. The original abstract is on the publisher’s page.

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