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Scientific Paper

Biosensor design utilizing particle-bound enzymes

PhD thesis 2020

Cassi Joanna Henderson

Apollo (University of Cambridge), 2020

View at publisher ↗

DOI 10.17863/cam.44912

Summary

Thesis on cheap biosensing elements for point-of-care tests in low-resource settings: recombinant fusion proteins bind to silica, even silica from sand, and are purified and immobilised in one step, with a fluorescent tag to follow the process by eye. The particle-bound reagents stayed active for two months dry at room temperature, and a new falling-particle device beat suspension and packed-bed formats.

Summary written by the openQCM team. The original abstract is on the publisher’s page.

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