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Scientific Paper

A simple and flexible model for laser-driven antibody – gold surface interactions: functionalization and sensing

Journal article 2016

Bartolomeo Della Ventura, Antonio Ambrosio, Annalisa Fierro, Riccardo Funari, Felice Gesuele, Pasquale Maddalena, Dirk Mayer, Massimo Pica Ciamarra, Raffaele Velotta, C. Altucci

ACS Applied Materials & Interfaces, 8 (33), 21762–21769, 2016

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DOI 10.1021/acsami.6b04449

Summary

A coarse-grained model of antibodies that describes, in a simple way, how they pack on a gold surface during laser-assisted functionalisation and how they then bind their antigen. Tested against experiments on gold functionalisation and immune recognition, the model matches the data closely and clarifies how antibodies arrange themselves on metals at the nanoscale.

Summary written by the openQCM team. The original abstract is on the publisher’s page.

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