# Quartz crystal microbalance experiments reveal structural changes in the Staphylococcus aureus biofilm in the presence of savirin

> Source page: https://openqcm.com/scientific-papers/quartz-crystal-microbalance-experiments-reveal-structural-changes-in-the-staphylococcus-aureus-biofilm-in-the-presence-of-savirin
> Markdown version for AI agents and readers of plain text. Site guide: https://openqcm.com/llms.txt · Everything in one file: https://openqcm.com/llms-full.txt

- Authors: Emilia M. Hudzik, Andrew J. Parnell, Jordan Petkov, Mark Geoghegan
- Journal: Results in Surfaces and Interfaces
- Year: 2025
- Volume: 19
- Pages: 100535
- DOI: 10.1016/j.rsurfi.2025.100535
- Instrument used: openQCM Sensors

## Abstract

ABSTRACT
 Quartz-crystal microbalance with dissipation (QCM-D) experiments show that green-fluorescent protein labelled Staphylococcus aureus adsorption to a gold QCM electrode is similar for a certain incubation period (here, 6 h) in the presence and absence of the quorum sensing inhibitor, savirin. After this period, cells continue to adsorb in the absence of savirin, but in its presence biofilm formation is severely compromised, with significant changes in the viscoelastic properties of the layer being observed.

---

openQCM by Novaetech S.r.l., Pompeii, Italy · Buy: https://store.openqcm.com/ · Contact: info@openqcm.com · https://openqcm.com/contacts/