# PB0747 Platelet Reactivity to Dengue and Zika Nonstructural Protein 1 (NS1)

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- Authors: A. Méndez, N. García-Larragoiti, S. López-Castañeda, G. Espinosa-Perez, Y. Chan-Kim, A. Reyes-Sandoval, M. Viveros-Sandoval
- Journal: Research and Practice in Thrombosis and Haemostasis
- Year: 2023
- Volume: 7
- Pages: 101332
- DOI: 10.1016/j.rpth.2023.101332
- Instrument used: openQCM 1

## Summary

Conference abstract on how human platelets react to non-structural protein 1 (NS1) of the dengue and Zika viruses. Platelet-rich plasma exposed to either protein showed the strongest activation markers by flow cytometry after 60 minutes, spreading and enlargement under atomic force microscopy, and a clear frequency change on QCM crystals coated with NS1; the two viral proteins activated platelets alike.

*Summary written by the openQCM team. The original abstract is on the publisher's page: https://doi.org/10.1016/j.rpth.2023.101332*

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